Top 500 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000694 Proline-rich region	685	8863	251	IPR000348 emp24/gp25L/p24	13	48
2	IPR000276 Rhodopsin-like GPCR superfamily	418	9970	252	IPR003599 Immunoglobulin subtype	13	33
3	IPR000719 Protein kinase	415	7387	253	IPR004254 Hly-III related proteins	13	22
4	IPR000504 RNA-binding region RNP-1 (RNA recognition motif)	230	2668	254	IPR000764 Uridine kinase	13	141
5	IPR003596 Immunoglobulin V-type	199	3670	255	IPR001134 Netrin, C-terminal	13	171
6	IPR000210 BTB	195	5324	256	IPR005595 Translocon-associated protein (TRAP), alpha subunit	13	17
7	IPR001680 WD-40 repeat	181	4269	257	IPR001107 Band 7 protein	13	157
8	IPR000533 Tropomyosin	180	1583	258	IPR001357 BRCT	13	201
9	IPR000008 C2	172	3166	259	IPR000904 SEC7-like	13	93
10	IPR000047 Helix-turn-helix motif, lambda-like repressor	166	2208	260	IPR001279 Beta-lactamase-like	13	26
11	IPR001806 Ras GTPase	159	2727	261	IPR005135 Endonuclease/exonuclease/phosphatase	13	88
12	IPR001841 Zinc finger, RING-type	148	1084	262	IPR003663 Sugar transporter	13	184
13	IPR000315 Zinc finger, B-box	145	3487	263	IPR000555 Mov34/MPN/PAD-1	13	67
14	IPR001092 Basic helix-loop-helix dimerisation region bHLH	111	535	264	IPR001159 Double-stranded RNA binding	13	123
15	IPR001870 B302, (SPRY)-like	109	1027	265	IPR001464 Annexin	13	1447
16	IPR001611 Leucine-rich repeat	102	1606	266	IPR001199 Cytochrome b5	13	136
17	IPR000048 IQ calmodulin-binding region	98	2282	267	IPR000566 Lipocalin-related protein and Bos/Can/Equ allergen	13	406
18	IPR002110 Ankyrin	97	2072	268	IPR000223 Peptidase S26A, signal peptidase I	13	136
19	IPR000152 Aspartic acid and asparagine hydroxylation site	92	8678	269	IPR000286 Histone deacetylase superfamily	12	113
20	IPR000372 Leucine-rich repeat, cysteine-rich flanking region, N-terminal	91	2558	270	IPR000433 Zinc finger, ZZ-type	12	266
21	IPR002048 Calcium-binding EF-hand	89	901	271	IPR000072 Platelet-derived growth factor (PDGF)	12	91
22	IPR000108 Neutrophil cytosol factor 2	84	2212	272	IPR001930 Peptidase M1, membrane alanine aminopeptidase	12	106
23	IPR001781 LIM, zinc-binding	82	3200	273	IPR002130 Peptidyl-prolyl cis-trans isomerase, cyclophilin type	12	115
24	IPR000767 Disease resistance protein	77	587	274	IPR002076 GNS1/SUR4 membrane protein	12	38
25	IPR000169 Peptidase, cysteine peptidase active site	74	1636	275	IPR001770 G-protein, gamma subunit	12	82
26	IPR001440 Tetratricopeptide TPR_1	72	1844	276	IPR000601 PKD	12	137
27	IPR001452 Src homology-3	72	1063	277	IPR001799 Ephrin	12	104
28	IPR000198 RhoGAP	71	742	278	IPR001881 EGF-like calcium-binding	12	364
29	IPR000104 Antifreeze protein, type I	71	988	279	IPR000270 Octicosapeptide/Phox/Bem1p	12	119
30	IPR001478 PDZ/DHR/GLGF	71	782	280	IPR001169 Integrin beta, C-terminal	12	496
31	IPR000219 DH	71	1028	281	IPR000920 Myelin P0 protein	12	145
32	IPR007087 Zinc finger, C2H2-type	70	870	282	IPR001759 Pentaxin	12	162
33	IPR000051 SAM (and some other nucleotide) binding motif	69	451	283	IPR000956 Stathmin	12	72
34	IPR000379 Esterase/lipase/thioesterase	68	743	284	IPR000542 Acyltransferase ChoActase/COT/CPT	12	49
35	IPR002198 Short-chain dehydrogenase/reductase SDR	67	1211	285	IPR001345 Phosphoglycerate/bisphosphoglycerate mutase	12	109
36	IPR001356 Homeobox	66	598	286	IPR001839 Transforming growth factor beta	12	67
37	IPR007086 Zinc finger, C2H2-subtype	63	1469	287	IPR000494 EGF receptor, L domain	11	248
38	IPR000742 EGF-like, type 3	63	2225	288	IPR000005 Helix-turn-helix, AraC type	11	9803
39	IPR000242 Tyrosine specific protein phosphatase	62	1724	289	IPR004344 Tubulin-tyrosine ligase	11	11
40	IPR000225 Armadillo	61	998	290	IPR000712 Apoptosis regulator Bcl-2, BH	11	60
41	IPR001304 C-type lectin	60	735	291	IPR003112 Olfactomedin-like	11	46
42	IPR001254 Peptidase S1 and S6, chymotrypsin/Hap	60	796	292	IPR000651 Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal	11	158
43	IPR001128 Cytochrome P450	59	2171	293	IPR000623 Shikimate kinase	11	130
44	IPR001849 Pleckstrin-like	58	321	294	IPR001290 Poly(ADP-ribose) polymerase, catalytic region	11	170
45	IPR001622 K+ channel, pore region	57	1125	295	IPR003034 DNA-binding SAP	11	50
46	IPR000357 HEAT	55	343	296	IPR002495 Glycosyl transferase, family 8	11	17
47	IPR000301 CD9/CD37/CD63 antigen	53	459	297	IPR011701 Major facilitator superfamily MFS_1	11	12
48	IPR001993 Mitochondrial substrate carrier	52	1106	298	IPR003347 Transcription factor jumonji/aspartyl beta-hydroxylase	11	25
49	IPR002126 Cadherin	51	1977	299	IPR005398 Tubby protein, N-terminal	11	30
50	IPR000980 SH2 motif	51	548	300	IPR000538 Link	11	268
51	IPR000159 RA	50	516	301	IPR001132 Dwarfin protein	11	67
52	IPR001660 Sterile alpha motif SAM	50	593	302	IPR001373 Cullin	11	49
53	IPR000626 Ubiquitin	49	447	303	IPR001293 Zinc finger, TRAF-type	11	139
54	IPR000248 Angiotensin II receptor	49	1888	304	IPR000403 Phosphatidylinositol 3- and 4-kinase, catalytic	11	76
55	IPR000449 Ubiquitin-associated	49	586	305	IPR000836 Phosphoribosyltransferase	11	50
56	IPR000884 Thrombospondin, type I	47	1133	306	IPR000697 EVH1	11	43
57	IPR000299 Band 4.1	47	726	307	IPR001401 Dynamin	11	123
58	IPR003598 Immunoglobulin C2 type	47	946	308	IPR005819 Histone H5	11	35
59	IPR000637 HMG-I and HMG-Y, DNA-binding	46	741	309	IPR000245 ATPase, V0 complex, proteolipid subunit C,	11	89
60	IPR000195 RabGAP/TBC	45	286	310	IPR000794 Beta-ketoacyl synthase	11	201
61	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	44	255	311	IPR000804 Clathrin adaptor complex, small chain	11	36
62	IPR000571 Zinc finger, CCCH-type	44	405	312	IPR000569 HECT	11	70
63	IPR000886 Endoplasmic reticulum targeting sequence	44	623	313	IPR001436 Alpha crystallin	11	74
64	IPR000306 Zinc finger, FYVE-type	43	450	314	IPR001346 Interferon regulatory factor	10	111
65	IPR000608 Ubiquitin-conjugating enzyme, E2	43	210	315	IPR001526 CD59 antigen	10	20
66	IPR001623 Heat shock protein DnaJ, N-terminal	43	339	316	IPR006594 Lissencephaly type-1-like homology motif	10	56
67	IPR001410 DEAD/DEAH box helicase	42	435	317	IPR001494 Importin-beta, N-terminal	10	30
68	IPR000340 Dual specificity protein phosphatase	40	385	318	IPR000909 Phosphatidylinositol-specific phospholipase C, X region	10	39
69	IPR000436 Sushi/SCR/CCP	40	1126	319	IPR000994 Peptidase M24	10	63
70	IPR001766 Fork head transcription factor	39	330	320	IPR003689 Zinc/iron permease	10	11
71	IPR000175 Sodium:neurotransmitter symporter	39	676	321	IPR000695 H+ transporting ATPase, proton pump	10	476
72	IPR003006 Immunoglobulin/major histocompatibility complex	39	727	322	IPR001876 Zinc finger, RanBP2-type	10	102
73	IPR001005 Myb, DNA-binding	39	463	323	IPR002350 Proteinase inhibitor I1, Kazal	10	90
74	IPR001507 Endoglin/CD105 antigen	38	261	324	IPR001461 Peptidase A1, pepsin	10	130
75	IPR001064 Beta and gamma crystallin	38	658	325	IPR006680 Amidohydrolase 1	10	43
76	IPR002035 von Willebrand factor, type A	38	542	326	IPR001388 Synaptobrevin	10	82
77	IPR001752 Kinesin, motor region	38	412	327	IPR000381 Inhibin, beta B subunit	10	213
78	IPR003656 Zinc finger, BED-type predicted	38	1376	328	IPR003680 Flavodoxin-like fold	10	11
79	IPR003597 Immunoglobulin C1 type	38	203	329	IPR000889 Glutathione peroxidase	10	49
80	IPR000500 Connexins	37	303	330	IPR001958 Tetracycline resistance protein	10	92
81	IPR001627 Semaphorin/CD100 antigen	37	339	331	IPR004182 GRAM	10	22
82	IPR000014 PAS	37	569	332	IPR002049 EGF-like, laminin	10	345
83	IPR001991 Sodium:dicarboxylate symporter	37	404	333	IPR000375 Dynamin central region	10	272
84	IPR000595 Cyclic nucleotide-binding	37	736	334	IPR000101 Gamma-glutamyltranspeptidase	10	145
85	IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit	37	900	335	IPR000058 Zinc finger, AN1-type	10	148
86	IPR000243 Peptidase T1A, proteasome beta-subunit	37	273	336	IPR001173 Glycosyl transferase, family 2	10	27
87	IPR001125 Recoverin	37	810	337	IPR006612 Zinc finger, C2CH-type	10	24
88	IPR000342 Regulator of G protein signalling	36	505	338	IPR003556 Claudin-14	10	111
89	IPR000327 POU	35	526	339	IPR000009 Protein phosphatase 2A regulatory subunit PR55	10	385
90	IPR000873 AMP-dependent synthetase and ligase	35	276	340	IPR000938 CAP-Gly	10	93
91	IPR000488 Death	35	1189	341	IPR000998 MAM	10	258
92	IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding	34	428	342	IPR002422 Amino acid/polyamine transporter II	10	34
93	IPR003604 Zinc finger, U1-type	34	472	343	IPR007052 CS	10	29
94	IPR000324 Vitamin D receptor	34	1016	344	IPR001463 Sodium:alanine symporter	10	104
95	IPR001810 Cyclin-like F-box	34	165	345	IPR002091 Aromatic amino acid permease	10	75
96	IPR000135 High mobility group box HMG1 and HMG2	34	300	346	IPR000850 Adenylate kinase	10	81
97	IPR000408 Regulator of chromosome condensation, RCC1	34	745	347	IPR002498 Phosphatidylinositol-4-phosphate 5-kinase	10	26
98	IPR002073 3'5'-cyclic nucleotide phosphodiesterase	33	386	348	IPR000300 Inositol polyphosphate related phosphatase	10	63
99	IPR001675 Glycosyl transferase, family 29	33	67	349	IPR001863 Glypican	10	18
100	IPR000215 Proteinase inhibitor I4, serpin	33	317	350	IPR004274 NLI interacting factor	10	43
101	IPR000003 Retinoid X receptor	32	1146	351	IPR003549 Claudin-3	9	175
102	IPR000330 SNF2-related	32	401	352	IPR001283 Allergen V5/Tpx-1 related	9	151
103	IPR000421 Coagulation factor 5/8 type, C-terminal	32	769	353	IPR001902 Sulphate anion transporter	9	50
104	IPR000483 Cysteine-rich flanking region, C-terminal	32	784	354	IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region	9	137
105	IPR000203 GPS	31	972	355	IPR001553 RecA bacterial DNA recombination	9	49
106	IPR003593 AAA ATPase	31	137	356	IPR001382 Glycoside hydrolase, family 47	9	111
107	IPR000164 Histone H3	31	561	357	IPR006634 TRAM, LAG1 and CLN8 homology	9	33
108	IPR000863 Sulfotransferase	30	45	358	IPR000641 CbxX/CfqX	9	110
109	IPR001664 Intermediate filament protein	30	395	359	IPR010450 Neurexophilin	9	9
110	IPR001715 Calponin-like actin-binding	30	166	360	IPR000756 Diacylglycerol kinase accessory region	9	258
111	IPR001390 Gamma-aminobutyric-acid A receptor, alpha subunit	30	908	361	IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45	9	10
112	IPR001214 Nuclear protein SET	30	456	362	IPR005024 Snf7	9	11
113	IPR004843 Metallophosphoesterase	29	375	363	IPR002016 Haem peroxidase, plant/fungal/bacterial	9	70
114	IPR001683 Phox-like	29	144	364	IPR000731 Sterol-sensing 5TM box	9	68
115	IPR001687 ATP/GTP-binding site motif A (P-loop)	29	284	365	IPR001753 Enoyl-CoA hydratase/isomerase	9	30
116	IPR001073 Complement C1q protein	29	274	366	IPR000204 Orexin receptor	9	351
117	IPR000253 Forkhead-associated	29	276	367	IPR005123 2OG-Fe(II) oxygenase	9	37
118	IPR000832 GPCR, family 2, secretin-like	29	742	368	IPR000239 GPCR kinase	9	126
119	IPR001594 Zinc finger, DHHC-type	29	146	369	IPR003137 Protease-associated PA	9	48
120	IPR000073 Alpha/beta hydrolase fold-1	29	378	370	IPR008906 HAT dimerisation	9	9
121	IPR000418 Ets	28	354	371	IPR000192 Aminotransferase, class V	9	42
122	IPR003961 Fibronectin, type III	28	152	372	IPR002017 Spectrin repeat	9	42
123	IPR001111 Transforming growth factor beta (TGFb), N-terminal	28	345	373	IPR001717 Anion exchange protein	9	349
124	IPR013026 Tetratricopeptide region	28	108	374	IPR001392 Clathrin adaptor complex, medium chain	9	96
125	IPR001965 Zinc finger, PHD-type	28	169	375	IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site	9	85
126	IPR007111 NACHT nucleoside triphosphatase	28	46	376	IPR000162 Metabotropic glutamate receptor	9	433
127	IPR007114 Major facilitator superfamily	27	68	377	IPR000664 Lethal(2) giant larvae protein	9	253
128	IPR000326 Phosphoesterase, PA-phosphatase related	27	108	378	IPR003653 Peptidase C48, SUMO/Sentrin/Ubl1	9	22
129	IPR000834 Peptidase M14, carboxypeptidase A	27	420	379	IPR001844 Chaperonin Cpn60	9	245
130	IPR004031 PMP-22/EMP/MP20 and claudin	27	183	380	IPR002259 Delayed-early response protein/equilibrative nucleoside transporter	9	62
131	IPR001472 Bipartite nuclear localization signal	27	199	381	IPR002610 Rhomboid-like protein	9	11
132	IPR002119 Histone H2A	27	352	382	IPR001807 Cl- channel, voltage gated	8	57
133	IPR001878 Zinc finger, CCHC-type	27	168	383	IPR000583 Glutamine amidotransferase, class-II	8	41
134	IPR001496 SOCS protein, C-terminal	27	724	384	IPR000513 5'3'-Exonuclease N- and I-domain	8	106
135	IPR001140 ABC transporter, transmembrane region	26	378	385	IPR003316 Transcription factor E2F/dimerisation partner (TDP)	8	12
136	IPR002394 Nicotinic acetylcholine receptor	26	574	386	IPR000749 ATP:guanido phosphotransferase	8	59
137	IPR000727 Target SNARE coiled-coil region	25	202	387	IPR000308 14-3-3 protein	8	133
138	IPR000313 PWWP	25	356	388	IPR006662 Thioredoxin-related	8	47
139	IPR000795 Protein synthesis factor, GTP-binding	25	439	389	IPR000407 Nucleoside phosphatase GDA1/CD39	8	35
140	IPR000068 Extracellular calcium-sensing receptor	25	756	390	IPR000074 Apolipoprotein A1/A4/E	8	14
141	IPR001951 Histone H4	25	232	391	IPR002999 Tudor	8	71
142	IPR000182 GCN5-related N-acetyltransferase	24	65	392	IPR004853 Protein of unknown function DUF250	8	16
143	IPR002559 Transposase, IS4	24	27	393	IPR001862 Membrane attack complex component/perforin/complement C9	8	26
144	IPR000629 ATP-dependent helicase, DEAD-box	24	243	394	IPR000941 Enolase	8	99
145	IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular	24	96	395	IPR001925 Porin, eukaryotic type	8	53
146	IPR008253 Marvel	24	40	396	IPR000817 Prion protein	8	82
147	IPR002209 Heparin-binding growth factor/Fibroblast growth factor	24	274	397	IPR000493 Inositol 1,4,5-trisphosphate-binding protein receptor	8	247
148	IPR001311 Solute-binding protein/glutamate receptor	24	331	398	IPR002155 Thiolase	8	84
149	IPR001757 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter	24	357	399	IPR000861 PKN/rhophilin/rhotekin rho-binding repeat	8	32
150	IPR000158 Cell division protein FtsZ	24	1360	400	IPR001285 Synaptophysin/synaptoporin	8	59
151	IPR000463 Cytosolic fatty-acid binding	24	229	401	IPR003000 Silent information regulator protein Sir2	8	20
152	IPR002293 Amino acid/polyamine transporter I	24	125	402	IPR001606 AT-rich interaction region	8	93
153	IPR000558 Histone H2B	23	256	403	IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal	8	33
154	IPR001164 Arf GTPase activating protein	23	336	404	IPR001564 Nucleoside diphosphate kinase	8	91
155	IPR001632 G-protein, beta subunit	23	762	405	IPR001917 Aminotransferase, class-II	8	36
156	IPR000772 Ricin B lectin	23	276	406	IPR001791 Laminin G	8	189
157	IPR000024 Frizzled CRD region	23	250	407	IPR001176 1-aminocyclopropane-1-carboxylate synthase	8	87
158	IPR000585 Hemopexin	23	514	408	IPR004129 Glycerophosphoryl diester phosphodiesterase	8	11
159	IPR005816 Secreted growth factor Wnt protein	22	230	409	IPR000089 Biotin/lipoyl attachment	8	83
160	IPR004000 Actin/actin-like	22	254	410	IPR001804 Isocitrate/isopropylmalate dehydrogenase	8	49
161	IPR000953 Chromo	22	216	411	IPR000322 Glycoside hydrolase, family 31	8	46
162	IPR000001 Kringle	22	921	412	IPR006087 SUR2-type hydroxylase/desaturase, catalytic region	8	19
163	IPR000233 Cadherin cytoplasmic region	22	732	413	IPR001365 Adenosine/AMP deaminase	8	39
164	IPR004827 Basic-leucine zipper (bZIP) transcription factor	22	80	414	IPR002893 Zinc finger, MYND-type	8	36
165	IPR005828 General substrate transporter	22	95	415	IPR001079 Galectin, galactose-binding lectin	8	29
166	IPR002086 Aldehyde dehydrogenase	22	210	416	IPR001619 Sec1-like protein	8	16
167	IPR001395 Aldo/keto reductase	22	305	417	IPR006663 Thioredoxin domain 2	8	19
168	IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II	21	738	418	IPR001026 Epsin, N-terminal	8	24
169	IPR001007 von Willebrand factor, type C	21	411	419	IPR000174 Interleukin-8 receptor	8	443
170	IPR001202 WW/Rsp5/WWP	21	214	420	IPR003409 MORN motif	8	94
171	IPR000644 CBS	21	274	421	IPR006055 Exonuclease	8	21
172	IPR000033 Low-density lipoprotein receptor, YWTD repeat	21	2500	422	IPR000183 Orn/DAP/Arg decarboxylase 2	8	152
173	IPR000086 NUDIX hydrolase	21	110	423	IPR000116 High mobility group proteins HMG-I and HMG-Y	8	47
174	IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase	21	164	424	IPR005522 Inositol polyphosphate kinase	8	9
175	IPR001509 NAD-dependent epimerase/dehydratase	21	232	425	IPR006025 Peptidase M, neutral zinc metallopeptidases, zinc-binding site	8	132
176	IPR000261 EPS15 homology (EH)	21	469	426	IPR001666 Phosphatidylinositol transfer protein	8	77
177	IPR000157 Toll-Interleukin receptor	20	626	427	IPR009886 HCaRG	8	9
178	IPR000716 Thyroglobulin type-1	20	168	428	IPR002129 Pyridoxal-dependent decarboxylase	8	46
179	IPR000480 Glutelin	20	213	429	IPR002345 Lipocalin	8	34
180	IPR001412 Aminoacyl-tRNA synthetase, class I	20	280	430	IPR001102 Protein-glutamine gamma-glutamyltransferase	8	45
181	IPR001190 Speract/scavenger receptor	20	507	431	IPR003406 Glycosyl transferase, family 14	8	9
182	IPR001778 Pollen allergen Poa pIX/Phl pVI, C-terminal	19	161	432	IPR003100 Argonaute and Dicer protein, PAZ	7	36
183	IPR001699 Transcription factor, T-box	19	230	433	IPR000759 Adrenodoxin reductase	7	141
184	IPR001487 Bromodomain	19	284	434	IPR001736 Phospholipase D/Transphosphatidylase	7	50
185	IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin	19	272	435	IPR004481 K+-dependent Na+/Ca+ exchanger related-protein	7	29
186	IPR000648 Oxysterol-binding protein	18	132	436	IPR006187 Claudin tight junction protein	7	30
187	IPR000867 Insulin-like growth factor-binding protein, IGFBP	18	284	437	IPR002052 N-6 Adenine-specific DNA methylase	7	58
188	IPR000837 Fos transforming protein	18	275	438	IPR003890 Initiation factor eIF-4 gamma, middle	7	29
189	IPR001039 MHC class I, alpha chain, alpha1 and alpha2	18	219	439	IPR000434 Polycystic kidney disease type 1 protein	7	100
190	IPR002659 Glycosyl transferase, family 31	18	20	440	IPR002348 Interleukin 1/heparin-binding growth factor	7	55
191	IPR000413 Integrins alpha chain	18	487	441	IPR006089 Acyl-CoA dehydrogenase	7	103
192	IPR000222 Protein phosphatase 2C	18	148	442	IPR002100 Transcription factor, MADS-box	7	71
193	IPR001023 Heat shock protein Hsp70	17	228	443	IPR004825 Insulin/IGF/relaxin	7	32
194	IPR001978 Troponin	17	23	444	IPR001040 Eukaryotic translation initiation factor 4E (eIF-4E)	7	22
195	IPR000971 Globin	17	189	445	IPR002909 Cell surface receptor IPT/TIG	7	34
196	IPR000190 AT1 angiotensin II receptor	17	747	446	IPR000366 Fungal pheromone mating factor STE2 GPCR	7	119
197	IPR008042 Retrotransposon, Pao	17	18	447	IPR001360 Glycoside hydrolase, family 1	7	68
198	IPR000717 Proteasome component region PCI	17	84	448	IPR000023 Phosphofructokinase	7	150
199	IPR001148 Carbonic anhydrase, eukaryotic	17	59	449	IPR013149 Alcohol dehydrogenase, zinc-binding	7	17
200	IPR000917 Sulfatase	17	72	450	IPR001220 Legume lectin, beta domain	7	42
201	IPR000095 PAK-box/P21-Rho-binding	17	226	451	IPR001201 PAP/25A core	7	60
202	IPR000333 Activin type II receptor	16	272	452	IPR005301 Mob1/phocein	7	9
203	IPR000467 D111/G-patch	16	130	453	IPR000426 Proteasome alpha-subunit	7	30
204	IPR000337 GPCR, family 3, metabotropic glutamate receptor-like	16	265	454	IPR002347 Glucose/ribitol dehydrogenase	7	32
205	IPR001734 Na+/solute symporter	16	68	455	IPR002125 CMP/dCMP deaminase, zinc-binding	7	24
206	IPR000425 Major intrinsic protein	16	175	456	IPR003859 Metazoa galactosyltransferase	7	11
207	IPR001682 Ca2+/Na+ channel, pore region	16	368	457	IPR010326 Exocyst complex component Sec6	7	8
208	IPR000038 Cell division/GTP binding protein	16	152	458	IPR003150 DNA-binding RFX	7	14
209	IPR004087 KH	16	187	459	IPR002223 Proteinase inhibitor I2, Kunitz metazoa	7	203
210	IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase	16	54	460	IPR006162 Phosphopantetheine attachment site	7	10
211	IPR001309 Caspase, p20 subunit	16	357	461	IPR002314 tRNA synthetase, class II (G, H, P and S)	7	119
212	IPR004020 Pyrin	16	56	462	IPR000547 7-Fold repeat in clathrin and VPS proteins	7	118
213	IPR001589 Actin-binding, actinin-type	16	658	463	IPR012937 Protein of unknown function DUF1693	7	10
214	IPR000560 Histidine acid phosphatase	16	314	464	IPR000698 Arrestin	7	79
215	IPR000205 NAD-binding site	16	254	465	IPR011021 Arrestin, N-terminal	7	24
216	IPR006020 Phosphotyrosine interaction region	16	38	466	IPR000402 ATPase, P-type cation exchange, beta subunit	7	32
217	IPR000282 Cytokine receptor class 2	15	206	467	IPR000118 Granulin	7	591
218	IPR000469 G-protein alpha subunit, group 12	15	389	468	IPR001089 Small chemokine, C-X-C	7	86
219	IPR001060 Cdc15/Fes/CIP4	15	155	469	IPR000034 Laminin B	7	597
220	IPR006703 AIG1	15	19	470	IPR007053 NC	7	8
221	IPR007632 Protein of unknown function DUF590	15	20	471	IPR000620 Protein of unknown function DUF6, transmembrane	7	14
222	IPR000910 HMG1/2 (high mobility group) box	15	128	472	IPR001101 Plectin repeat	7	429
223	IPR002123 Phospholipid/glycerol acyltransferase	15	53	473	IPR005026 Guanylate-kinase-associated protein	7	7
224	IPR000020 Anaphylatoxin/fibulin	15	577	474	IPR002946 Intracellular chloride channel	7	65
225	IPR000679 Zinc finger, GATA-type	15	154	475	IPR001429 ATP P2X receptor	7	263
226	IPR001630 cAMP response element binding (CREB) protein	15	170	476	IPR000007 Tubby	7	149
227	IPR001368 TNFR/CD27/30/40/95 cysteine-rich region	15	225	477	IPR002108 Actin-binding, cofilin/tropomyosin type	7	35
228	IPR001270 Chaperonin clpA/B	14	141	478	IPR002014 VHS	7	65
229	IPR000577 Carbohydrate kinase, FGGY	14	411	479	IPR001017 Dehydrogenase, E1 component	7	25
230	IPR001751 Calcium-binding protein, S-100/ICaBP type	14	126	480	IPR001247 Exoribonuclease	7	23
231	IPR001315 Caspase Recruitment	14	126	481	IPR004365 nucleic acid binding, OB-fold, tRNA/helicase-type	7	15
232	IPR006670 Cyclin	14	39	482	IPR003594 ATP-binding region, ATPase-like	7	46
233	IPR000591 Pleckstrin/ G-protein, interacting region	14	145	483	IPR000640 Elongation factor G, C-terminal	7	128
234	IPR002229 Blood group Rhesus C/E and D polypeptide	14	182	484	IPR001209 Ribosomal protein S14	7	42
235	IPR001506 Peptidase M12A, astacin	14	153	485	IPR000866 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen	7	28
236	IPR001179 Peptidylprolyl isomerase, FKBP-type	14	165	486	IPR000690 Zinc finger, C2H2-type matrin	7	67
237	IPR001503 Glycosyl transferase, family 10	14	15	487	IPR004241 Light chain 3 (LC3)	7	10
238	IPR001222 Transcription factor TFIIS	14	484	488	IPR012496 TMC	7	11
239	IPR001163 Like-Sm ribonucleoprotein, core	14	28	489	IPR000584 Dihydropyridine sensitive L-type calcium channel, beta subunit	7	140
240	IPR000082 SEA	14	314	490	IPR000718 Peptidase M13, neprilysin	7	71
241	IPR001194 DENN	14	94	491	IPR003107 RNA-processing protein, HAT helix	7	98
242	IPR000331 Rap/ran-GAP	14	86	492	IPR001071 Cellular retinaldehyde binding/alpha-tocopherol transport	7	116
243	IPR004367 Cyclin, C-terminal	14	74	493	IPR005331 Chondroitin 4-O-sulfotransferase	7	8
244	IPR000010 Proteinase inhibitor I25, cystatin	14	131	494	IPR001236 Lactate/malate dehydrogenase	7	104
245	IPR000859 CUB	14	243	495	IPR001523 Paired box protein, N-terminal	7	78
246	IPR004299 Membrane bound O-acyl transferase, MBOAT	13	24	496	IPR000562 Type II fibronectin, collagen-binding	7	344
247	IPR000923 Blue (type 1) copper domain	13	66	497	IPR003877 SPla/RYanodine receptor SPRY	6	29
248	IPR002996 Cytokine receptor, common beta/gamma chain	13	73	498	IPR002087 Anti-proliferative protein	6	55
249	IPR002917 GTP-binding protein, HSR1-related	13	92	499	IPR004294 Carotenoid oxygenase	6	11
250	IPR002111 Cation (not K+) channel, TM region	13	65	500	IPR000683 Oxidoreductase, N-terminal	6	13

View top 40 InterPro hits

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